Custom Peptides
Cayman Chemical 1 2DIarachIdonylsnglycero 10mg
A phospholipid containing the polyunsaturated long-chain (20:4) arachidonic acid inserted at the sn-1 and sn-2 positions
Cayman Chemical C18 CeramIded18 118 0 10mg
A bioactive sphingolipid; the primary short-chain ceramide found in brain tissue; synthesis is regulated by Lass1 in mice; positively correlated to body mass index and inversely related to insulin sensitivity; reduces cell growth in UM-SCC-22A squamous cell carcinoma cells; selectively downregulated in 32 squamous cell carcinoma tumor tissues; positively correlated to body mass index and inversely related to insulin sensitivity in type 2 diabetic patients
Cayman Chemical SalvInorIn B 10mg
An analytical reference standard categorized as a diterpene; a presumptive metabolite of salvinorin A; has been found in S. divinorum, a plant with hallucinogenic properties; intended for research and forensic applications
Cayman Chemical ATRACTYLODIN 10MG
A polyethylene alkyne with diverse biological activities; inhibits NAAA (IC50 = 2.81 µM for the human enzyme); increases levels of palmitoyl ethanolamide and oleoyl ethanolamide in LPS-stimulated BV-2 cells at 10 µM; cytotoxic to CL-6 and HuCC-T1 cells (IC50s = 41.66 and 38.78 µM, respectively); increases the gastric emptying rate in mice at 10 mg/kg; decreases pulmonary edema in a mouse model of LPS-induced acute lung injury at 40 and 80 mg/kg
Cayman Chemical SLP7111228hydrochlorIde 10mg
A potent and selective SPHK1 inhibitor (Kis = 0.048 and >10 μM for SPHK1 and 2, respectively); induces a concentration-dependent decrease in U937 cells; decreases blood levels of S1P in a dose-dependent manner in rats
Cayman Chemical SMAP 29ovIntrIfluoroace 10mg
An antimicrobial peptide; bactericidal to P. aeruginosa strain PAO1 under low- and high-salt conditions in an energy-dependent luminescence assay (EC50s = 0.05 and 0.06 µM, respectively)
Cayman Chemical 4-MethylamInontIpyrInhydr 10mg
A major active metabolite of metamizole; inhibits A23187-induced PGE2 production in isolated mouse peritoneal macrophages at 0.1 mM; increases the paw withdrawal threshold in a rat model of carrageenan-induced hyperalgesia at 160 UG/paw; reduces LPS-induced pyrexia in rats at 60, 90, and 120 mg/kg; a potential impurity found in commercial preparations of metamizole
Cayman Chemical ArtepIlIn C 10mg
A prenylated cinnamic acid with diverse biological activities; selectively inhibits AKR1C3 (IC50 = 1 µM) over AKR1C1, AKR1C2, and AKR1C4 at 100 µM; inhibits lipid peroxidation in isolated human erythrocytes; induces calcium influx in HEK293T cells expressing human TRPA1 at 10 µM, an effect that can be blocked by HC-030031; cytotoxic to HT-1080 and 26-L5 cells (IC50s = 45.47 and 59.32 UG/ml, respectively); active against C. albicans, E. floccosum, T. rubrum, methicillin-sensitive S. aureus, and MRSA (MICs = 250, 50, 125, 250, and 250 UG/ml, respectively); decreases carrageenan-induced peritoneal leukocyte infiltration in mice at 1 and 10 mg/kg
Cayman Chemical Metoprololtartrate 10mg
An analytical reference standard categorized as a β1-adrenergic receptor blocker; intended for use in analytical forensic applications
Cayman Chemical 13methyl PentadecnoIc ACD 10mg
A methylated fatty acid methyl ester; has been found in the bioactive fraction of A. malabarica extract, C. variabilis microalgae, and baboon liver
Cayman Chemical CID-2745687 10mg
A reversible, competitive antagonist of GPR35, blocking activation by the synthetic agonist pamoic acid with a Ki of 12.8 nM; less potently blocks activation of GPR35 by zaprinast (IC50 = 160 nM); shows ~57-fold selectivity for GPR35 over the related receptor GPR55 (IC50 = 9.08 µM)
Cayman Chemical 4 5 7-TrImethoxyflavon 10mg
A flavonoid with diverse biological activities; inhibits AChE and BChE by 47.1 and 46.2%, respectively, in a cell-free assay at 0.1 mg/ml; scavenges radicals in a TEAC assay at 1 and 10 µM; inhibits RANKL-induced osteoclastic differentiation of RAW 264.7 cells at 10 µM; stimulates chloride secretion in Calu-3 cells
Cayman Chemical TerbuthylazIn 10mg
A triazine herbicide; active against a variety of broadleaf and grass weeds in combination with S-metolachlor; has been found in surface groundwater and soil samples
Cayman Chemical 1-ThIoglycerol 10mg
A reagent used in fluorescence, spectroscopy, and microbiology techniques; provides precise control in varying the shell size of ultrasmall quantum dots; used as a capping agent in spectroscopy; stimulates porphyrin synthesis and increases glutamyl-tRNA reductase activity in E. coli grown in an aerobic environment; previously used in hair permanents
Cayman Chemical Esmolol-d7hydrochlorIde 10mg
An internal standard for the quantification of esmolol by GC- or LC-MS